Many of today's equestrian businesses still use, in terms of management and training, methods based on insights from the last century. If we, as a profession, want to continue supporting equestrian sports in a positive way over the next decade, it is essential to revise these methods and provide horse owners with sufficient practical tools to do so.
Nutrition plays a vital role within managing horse welfare; a proper ration is essential. Although
HorStem is the first registered veterinary medicine based on mesenchymal stem cells obtained from the umbilical cord of horses. Stem cells reduce lameness in horses with mild to moderate degenerative joint disease (OA).
It is a ready-to-use, sterile, injectable suspension for intra-articular use in horses. Each vial contains 15 million active stem cells, more than enough to achieve the minimum effective dose in the joint regardless of the degree of inflammation or the patient's immune system status.
The mechanism of action of HorStem is illustrated in the figure on the right. Mesenchymal stem cells are activated in the synovium by inflammatory cytokines. In response, they secrete anti-inflammatory cytokines such as Prostaglandin E2 (PGE2).
While PGE2 is primarily known for its pro-inflammatory effects, it also plays a crucial role in regulating inflammation. It is one of the major immunomodulatory cytokines in the body.
When applied to horses with OA, HorStem inhibits T-cell proliferation, reduces the production of pro-inflammatory cytokines like TNF-alpha, and decreases the presence of matrix metalloproteinases (MMPs) that contribute to the breakdown of cartilage's extracellular matrix. Studies have shown that these effects are mediated by PGE2. (1)
Moreover, umbilical cord-derived mesenchymal stem cells stimulate the production of anti-inflammatory cytokines such as IL-4, IL-5, IL-10, and TGF-beta. As the inflammatory response ceases
Expansion adds new countries to Grovet's existing PulseVet distribution coverage and enables launch of the TRUFORMA® equine platform in Europe
ANN ARBOR, MI / ACCESSWIRE / October 3, 2024 / Zomedica Corp. (NYSE American:ZOM) ("Zomedica" or the "Company"), a veterinary health company offering point-of-care diagnostics and therapeutic products for equine and companion animals, today announced the expansion of its distribution partnership in Europe with Grovet, a leading equine-focused veterinary distributor.
The terms of the updated agreement offer Grovet equine distribution rights for Zomedica's equine PulseVet® and TRUFORMA product platforms throughout most of Europe. Grovet will exclusively distribute these equine products in 27 countries, including Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary,
Meet our Grovet team at...
Aug. 15 to 17
Sept. 6 to 7
Sept. 11 to 14
Sept. 17 to 20
We are looking forward to meeting you!
At Grovet, we are driven to exceed equine veterinarian expectations and are constantly developing our product line to continue to optimize it. Our supplements for horses are of high quality and are formulated based on scientific evidence. Grovet offers a wide range of complementary feeds to support the management of sport horses, read more below.
For filling the horse's hoof when taking X-rays. Try it now!
Rediscover the classic with discount! Buy 2, get 1 for free!*
*This promotion is valid until July 19 2024
Osteoarthritis (OA) ist ein chronischer, degenerativer Entzündungsprozess in den Gelenken, der mit Knorpelschäden und abnormalem Knochenwachstum einhergeht. Sie ist eine der Hauptursachen für Lahmheiten bei Pferden; in Studien konnten 60 % der Lahmheiten auf OA zurückgeführt werden.
Die Behandlung der Arthrose zielt häufig darauf ab, die Entzündung zu verringern und die Schmerzen zu kontrollieren. Dies wird durch die Behandlung mit nichtsteroidalen Entzündungshemmern (NSAIDs) oder intraartikulären Kortikosteroiden (COs) erreicht. Heutzutage wird eine zunehmende Zahl von Therapien angewandt, die den Knorpelstoffwechsel und die Gelenkfunktion beeinflussen sollen, wie Hyaluronsäure (HA), polysulfatierte Glykosaminoglykane (PSGAG) und Pentosanpolysulfat.
In den letzten Jahren sind Orthobiologika, d. h. biologische Substanzen, die zur Behandlung orthopädischer Erkrankungen eingesetzt werden, zunehmend in
At Grovet, we have a wide range of unique brands, including IceHorse. The IceHorse product line is specifically designed for injury prevention and rehabilitation. IceHorse has a wide range of therapeutic wraps and head boots for cold and heat therapy. In this blog, we would like to introduce IceHorse's product line.
The IceHorse Cold Capsule Inserts mold to the body and provide continuous cold therapy for more than two hours per application. The inserts are reusable, you can put the packs back in the freezer and within a few hours they are ready to use again. In addition, they are designed so that no liquid can flow in or out. IceHorse's product range also includes Deep
Grovet is moving, to a new improved location! This move is a significant step forward in our ongoing commitment to providing you with the best possible service and further growing our business.
We understand that changes can sometimes raise questions, so we want to assure you that we are taking every measure to ensure a smooth transition. Below are some key points you should know about our relocation:
CLOSED
Due to the move, we will be closed from May 29 to May 31 2024. No orders will be processed or shipped during this period. However, it is possible to place your order. Orders placed before 2:00 p.m (May 28) will be shipped the same day. Order wider than usual to avoid missing out.
Orders placed after 2:00 p.m. (May 28) will be processed again from June 3 2024, please allow for some delay.
NEW ADDRESS
