While nutrition has historically been considered the appropriate amount of nutrients needed for energy, to maintain weight and promote growth, the majority of dietary effects may actually occur in ways that are, in fact, not always obvious to the naked eye. This is until there is evidence of a health concern. But what is consumed through the daily diet really begins by influencing at the level of the cell and has a profound effect on each and every living animal. What the horse consumes has the ability to benefit so many areas of health, including immunity, athletic performance, reproduction, metabolism, longevity and more. But what the horse takes in daily also has the ability to interfere or take away from the health and well-being of the animal. A specific fat, the omega-3 fatty acid, has a significant role in equine nutrition due to its multiple applications on numerous health
Grovet Administrator
- Posted: November 04, 2024Read more »
- Posted: October 10, 2024Read more »
HorStem is the first registered veterinary medicine based on mesenchymal stem cells obtained from the umbilical cord of horses. Stem cells reduce lameness in horses with mild to moderate degenerative joint disease (OA).
It is a ready-to-use, sterile, injectable suspension for intra-articular use in horses. Each vial contains 15 million active stem cells, more than enough to achieve the minimum effective dose in the joint regardless of the degree of inflammation or the patient's immune system status.
How does HorStem work?
The mechanism of action of HorStem is illustrated in the figure on the right. Mesenchymal stem cells are activated in the synovium by inflammatory cytokines. In response, they secrete anti-inflammatory cytokines such as Prostaglandin E2 (PGE2).
While PGE2 is primarily known for its pro-inflammatory effects, it also plays a crucial role in regulating inflammation. It is one of the major immunomodulatory cytokines in the body.
When applied to horses with OA, HorStem inhibits T-cell proliferation, reduces the production of pro-inflammatory cytokines like TNF-alpha, and decreases the presence of matrix metalloproteinases (MMPs) that contribute to the breakdown of cartilage's extracellular matrix. Studies have shown that these effects are mediated by PGE2. (1)
Moreover, umbilical cord-derived mesenchymal stem cells stimulate the production of anti-inflammatory cytokines such as IL-4, IL-5, IL-10, and TGF-beta. As the inflammatory response ceases
- Posted: October 03, 2024Read more »
Expansion adds new countries to Grovet's existing PulseVet distribution coverage and enables launch of the TRUFORMA® equine platform in Europe
ANN ARBOR, MI / ACCESSWIRE / October 3, 2024 / Zomedica Corp. (NYSE American:ZOM) ("Zomedica" or the "Company"), a veterinary health company offering point-of-care diagnostics and therapeutic products for equine and companion animals, today announced the expansion of its distribution partnership in Europe with Grovet, a leading equine-focused veterinary distributor.
The terms of the updated agreement offer Grovet equine distribution rights for Zomedica's equine PulseVet® and TRUFORMA product platforms throughout most of Europe. Grovet will exclusively distribute these equine products in 27 countries, including Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary,
- Posted: September 30, 2024Read more »
Meet our team at...
Oct. 10 to 11
Oct. 24 to 25
Oct. 26 to 27
31 oktober t/m 2 november
Sports Medicine and Rehabilitation Days - NL
We look forward to meeting you! - Posted: September 09, 2024
- Posted: August 12, 2024Read more »
What is the Pro-Stride system?
Pro-Stride, Restigen and Centrate are medical devices that allow blood from horses to be processed into solutions that can be used for therapy. Autologous protein solution (APS), PRP and concentrates from bone marrow aspirate can be prepared in less than 30 minutes. The system is suitable for outpatient use and incubation is not required. The closed system makes it a safe procedure with minimal risk of contamination.Platelet-rich plasma, Restigen PRP
Restigen PRP is used primarily for tendon
- Posted: July 29, 2024Read more »
Meet our Grovet team at...
Aug. 15 to 17
Sept. 6 to 7
Sept. 11 to 14
Sept. 17 to 20
We are looking forward to meeting you!
- Posted: June 28, 2024Read more »
At Grovet, we are driven to exceed equine veterinarian expectations and are constantly developing our product line to continue to optimize it. Our supplements for horses are of high quality and are formulated based on scientific evidence. Grovet offers a wide range of complementary feeds to support the management of sport horses, read more below.
Our all-in-one supplement Artilium Complete with improved formula
- Posted: June 24, 2024Read more »
Grovet's hoof plaster, renewed and improved.
For filling the horse's hoof when taking X-rays. Try it now!
- For shadow-free X-ray images of the hoof
- Comes out of the jar effortlessly
- Easy to apply under the horse's sole
- Reusable
Rediscover the classic with discount! Buy 2, get 1 for free!*
*This promotion is valid untill July 19 2024.
- Posted: May 31, 2024Read more »
Osteoarthritis (OA) is a chronic, degenerative inflammatory process in the joints involving damage to cartilage and abnormal bone growth. It is a major cause of lameness in horses; in some studies, 60% of the lameness’s could be related to OA.
Treatment of osteoarthritis often aims to reduce inflammation and control pain. This is achieved by treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) or intra-articular corticosteroids (COs). Nowadays, an increasing number of therapies are applied that are intended to affect cartilage metabolism and joint function, such as hyaluronic acid (HA), polysulphated glycosaminoglycans (PSGAG) and pentosanpolysulphate.
In recent years, an increasing focus has been on orthobiologics, which are biological substances used to treat orthopaedic conditions. In OA, autologous substances such as autologous protein solution (APS) or stem cells from bone marrow are used, for example. Allogeneic orthobiologics, obtained