Equilis Prequenza TE 10 x 1 injector

Composition:

Per dose of 1 ml:
Active substances:
Equine influenza virus strains:
A/equine-2/South Africa/4/03..........................50 AU¹
A/equine-2/Newmarket/2/93...........................50 AU
Tetanus toxoid...................................................40 Lf^2
1Antigenic units
²Flocculation equivalents; corresponds with ≥ 30 IU/ml guinea pig serum in the Ph.Eur. potency test

Adjuvants:
Purified Saponin...............................................375 micrograms
Cholesterol........................................................125 micrograms
Phosphatidylcholine.........................................62.5 micrograms

Indications:

Active immunization of horses from 6 months of age against equine influenza to reduce clinical signs and virus excretion after infection, and active immunization against tetanus to prevent mortality.
Influenza
Onset of immunity: 2 weeks after the primary vaccination course
Duration of immunity: 5 months after the primary vaccination course
                                       12 months after the first revaccination
Tetanus
Onset of immunity: 2 weeks after primary vaccination course
Duration of immunity:17 months after the primary vaccination course
                                       24 months after the first revaccination

Contraindications:

None

Side-effects:

A diffuse hard or soft swelling (max. diameter 5 cm) may occur at the injection site, regressing within 2 days. In very rare cases a local reaction exceeding 5 cm and possibly persisting longer than 2 days may occur. Pain at the injection site can occur in rare cases which may result in temporary functional discomfort (stiffness). In very rare cases, fever, sometimes accompanied by lethargy and inappetence, may occur for 1 days, and up to 3 days in exceptional circumstances.

Dosage and administration:

Equilis Prequenza TE is for intramuscular use.

Vaccination schedule:
Primary vaccination course
Administer one dose (1 ml), by strict intramuscular injection, according to the following schedule:
-          Primary vaccination course first injection from 6 months of age, second injection 4 weeks later.
Revaccination
Influenza
It is recommended that a single booster dose should only be administered to horses that have already received a primary vaccination course using vaccines that contain the same types of equine influenza virus included in this vaccine. A primary vaccination course may be considered necessary in horses that have not been suitably primed.

The first revaccination (third dose) against equine influenza is given 5 months after the primary vaccination course. This revaccination results in immunity to equine influenza lasting at least 12 months 

The second revaccination is given 12 months after the first revaccination.

The alternate use, at 12 months interval, of a suitable vaccine against equine influenza, containing the strains A/equine-2/South Africa/4/03 and A/equine-2/Newmarket-2/93, is recommended to maintain immunity levels for the influenza component.

Tetanus
The first revaccination is given not later than 17 months after the primary vaccination course. Therafter a maximum interval of two years is recommended.

In case of increased infection risk or insufficient colostrum intake, and additional initial injection can be given at the age of 4 months followed by the full vaccination programme (Primary vaccination course at 6 months of age and 4 weeks later).

Concurrent active and passive immunization (emergency vaccination)
The vaccine can be used together with Tetanus-Serum from Intevet for treatment of injured horses that have not been immunized against tetanus. In that case, the first dose (V1) of vaccine can be given concurrently with the appropriate prophylactic dose of Tetanus-Serum from Intervet at a separate injection site, using separate syringes and needles. This will lead to a passive protection against tetanus for at least 21 days after concurrent administration. The second dose of vaccine (V2) should be administered 4 weeks later. A third vaccination Equilis Prequenza Te should be repeated at least four weeks later. Concurrent use of Equilis Prequenza Te and Tetanus-Serum from Intervet may reduce active immunity against tetanus compared to hores vaccinated with Equilis Prequenza Te in the absence of tetanus antitoxin serum.

0Special precautions for storage

Store at 2-8 °C, protected from light. Do not freeze.